LaBonne is president of the Society for Developmental Biology and the Erastus Otis Haven professor of molecular biosciences at Northwestern University. Imagine a world without lifesaving medicines, ...

Every year, millions of animals are used in laboratories, and for many people, the image is immediate and uncomfortable: ...

While Catharine Krebs was working in a human-genetics laboratory during her PhD at the University of California, Los Angeles, there was a line that she got used to seeing at the end of papers: “These ...

In recent months, the Food and Drug Administration and National Institutes of Health have announced new initiatives to reduce and replace animal testing in biomedical research. Central to these ...

Suggested Citation: "1 Introduction to Precision Medicine and Animal Models." National Academies of Sciences, Engineering, and Medicine. 2018. Advancing Disease Modeling in Animal-Based Research in ...

A recent op-ed in The Hill praising the National Institutes of Health’s new initiative to promote human-based technologies as a “major victory for animal ethics in science” oversimplifies a far more ...

Every year, more than 100 million animals are used globally in biomedical research, yet over 90% of drugs that appear effective in animal trials fail during human clinical testing. 1 This staggering ...

A fundamental challenge in preclinical research is accurately predicting human responses using conventional animal models. Traditional approaches often fail to adequately model human disease, creating ...

The Food and Drug Administration and National Institutes of Health held a joint workshop July 7 on reducing animal testing in research, strikingly announcing that “NIH will no longer seek proposals ...

Animal testing remains a fundamental part of biomedical research. But as funding evaporates, mice, rats and even monkeys may be euthanized. By Emily Anthes On April 1, the Trump administration’s ...