For decades, the dream of fixing harmful mutations in mitochondrial DNA felt out of reach. Scientists have long known these mutations cause serious diseases that pass down only through mothers. They ...

Learn more about a new experimental procedure that uses cancer cells’ DNA repair system against itself to make drug-resistant ...

From the time we are conceived and through old age, genetic mutations accumulate in all our tissues, eluding the body’s typically efficient DNA repair machinery and potentially affecting our health ...

A genomic study of the largest pediatric and adult aplastic anemia cohort genetically profiled to date, finds that protective ...

A new prime assembly technique inserts DNA segments up to 11,000 base pairs into the genome, enabling correction of thousands ...

Some genetic disorders-such as cystic fibrosis, hemophilia and Tay Sachs disease-involve many mutations in a person's genome, often with enough variation that even two individuals who share the same ...

Mice pups conceived with in vitro fertilization (IVF) in the lab have slightly increased rates of DNA errors, or mutations, compared to pups conceived naturally, a new study on artificial reproductive ...

Mutations in the BRCA1 gene that are either inherited (germline) or acquired (somatic) might not be key to the initiation of prostate cancer, as previously thought, suggests the first study of its ...

A new microfluidic chip simplifies detecting and quantifying DNA by analyzing electrical impedance signals that vary based on DNA flowing across a biosensor inside the chip. The proof-of-concept ...

A reanalysis of whole-genome data from 130 children conceived after the Chernobyl disaster has identified a statistically significant increase in a specific type of DNA mutation in the offspring of ...