Johns Hopkins researchers have developed a powerful new AI tool called Splam that can identify where splicing occurs in genes—an advance that could help scientists analyze genetic data with greater ...

DURHAM, N.C.— Genes talk to themselves and to each other to control how a given cell manufactures proteins. But variation in the control of the same gene in two different tissues may contribute to ...

Genes are like instructions, but with options for building more than one thing. Daniel Larson, senior investigator at the National Cancer Institute, studies this gene "splicing" process, which happens ...

HOUSTON (Oct. 17, 2005) – The gene responsible for Rett syndrome, a devastating neurological disease found mostly in girls, not only silences some genes but in combination with another also regulates ...

Identifying splice sites is also important in annotating genomes, which involves identifying which parts of our DNA are functional and what roles they play in the body. One familiar application of ...

Approximately 2 to 6% of familiar dilated cardiomyopathy (DCM) cases are caused by inherited mutations in the RBM20 gene, which encodes the RNA binding motif 20 (RBM20), a splicing factor that ...