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恶性疟原虫裂殖子表面蛋白基因型与抗原多样性在马拉维儿童重症 ...
本研究针对恶性疟原虫(P. falciparum)基因多样性在疟疾致病机制中的作用,通过分析马拉维儿童重症疟疾患者的MSP-1和MSP-2基因多态性,发现脑型疟疾(CM)与严重贫血型疟疾(SMA)患者携带的寄生虫基因型存在显著差异。研究证实MSP-2 FC27型与SMA相关,而MSP-1 K1型在CM患者 ...
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