Functional gastrointestinal disorders (FGIDs), including irritable bowel syndrome, functional dyspepsia, and chronic visceral pain syndromes, affect a ...

Parkinson's and Alzheimer's diseases are the two most common neurodegenerative disorders, affecting millions of people worldwide. Published in the Journal of Neuroscience, new research from the ...

Researchers at VIB-KU Leuven shed light on an unusual signaling pathway that orchestrates synaptic structure and function during brain development. Leuven, 20 May 2025 - Researchers from the lab led ...

Transcriptomic analyses revealed thousands of differentially expressed genes in the brain, with synaptogenesis signaling emerging as the most significantly disrupted pathway—even at the lowest ...

Low-dose ephedrine disrupts synaptic signaling and behavior in adult zebrafish. Schematic overview of the experimental design, key neurotoxic mechanisms, and functional outcomes following chronic ...

Researchers discovered that suppressing BMP signaling in astrocytes reduces seizures and restores brain balance in Fragile X syndrome models.

Researchers from the lab led by Prof. Joris De Wit (VIB-KU Leuven) have discovered an important clue to how connections between brain cells, known as synapses, mature. These new findings, published in ...

Neuroplasticity and development have traditionally focused on synaptic mechanisms as the primary substrates of circuit remodeling. However, recent advances ...